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miR-132-3p is a positive regulator of alpha-cell mass and is downregulated in obese hyperglycemic mice
OBJECTIVE: Diabetes is a complex disease implicating several organs and cell types. Within the islets, dysregulation occurs in both alpha- and beta-cells, leading to defects of insulin secretion and increased glucagon secretion. Dysregulation of alpha-cells is associated with transcriptome changes....
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437597/ https://www.ncbi.nlm.nih.gov/pubmed/30711402 http://dx.doi.org/10.1016/j.molmet.2019.01.004 |