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Membrane metallo-endopeptidase (Neprilysin) regulates inflammatory response and insulin signaling in white preadipocytes

OBJECTIVE: Accumulation of visceral white adipose tissue (WAT) associates with insulin resistance, adipose tissue inflammation, and metabolic syndrome, whereas accumulation of subcutaneous WAT may be protective. We aimed to identify molecular mechanisms that might provide mechanistic insights underl...

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Detalles Bibliográficos
Autores principales: Ramirez, Alfred K., Dankel, Simon, Cai, Weikang, Sakaguchi, Masaji, Kasif, Simon, Kahn, C. Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437599/
https://www.ncbi.nlm.nih.gov/pubmed/30795914
http://dx.doi.org/10.1016/j.molmet.2019.01.006