Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()

Marine sponges of the genus Stelletta are well known as rich sources of diverse and complex biologically relevant natural products, including alkaloids, terpenoids, peptides, lipids, and steroids. Some of these metabolites, with novel structures and promising biological activities, have attracted a...

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Autores principales: Wu, Qihao, Nay, Bastien, Yang, Min, Ni, Yeke, Wang, Hong, Yao, Ligong, Li, Xuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437601/
https://www.ncbi.nlm.nih.gov/pubmed/30972275
http://dx.doi.org/10.1016/j.apsb.2018.10.003
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author Wu, Qihao
Nay, Bastien
Yang, Min
Ni, Yeke
Wang, Hong
Yao, Ligong
Li, Xuwen
author_facet Wu, Qihao
Nay, Bastien
Yang, Min
Ni, Yeke
Wang, Hong
Yao, Ligong
Li, Xuwen
author_sort Wu, Qihao
collection PubMed
description Marine sponges of the genus Stelletta are well known as rich sources of diverse and complex biologically relevant natural products, including alkaloids, terpenoids, peptides, lipids, and steroids. Some of these metabolites, with novel structures and promising biological activities, have attracted a lot of attention from chemists seeking to perform their total synthesis in parallel to intensive biological studies towards new drug leads. In this review, we summarized the distribution of the chemically investigated Stelletta sponges, the isolation, synthesis and biological activities of their secondary metabolites, covering the literature from 1982 to early 2018.
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spelling pubmed-64376012019-04-10 Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects() Wu, Qihao Nay, Bastien Yang, Min Ni, Yeke Wang, Hong Yao, Ligong Li, Xuwen Acta Pharm Sin B Review Marine sponges of the genus Stelletta are well known as rich sources of diverse and complex biologically relevant natural products, including alkaloids, terpenoids, peptides, lipids, and steroids. Some of these metabolites, with novel structures and promising biological activities, have attracted a lot of attention from chemists seeking to perform their total synthesis in parallel to intensive biological studies towards new drug leads. In this review, we summarized the distribution of the chemically investigated Stelletta sponges, the isolation, synthesis and biological activities of their secondary metabolites, covering the literature from 1982 to early 2018. Elsevier 2019-03 2018-10-16 /pmc/articles/PMC6437601/ /pubmed/30972275 http://dx.doi.org/10.1016/j.apsb.2018.10.003 Text en © 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Wu, Qihao
Nay, Bastien
Yang, Min
Ni, Yeke
Wang, Hong
Yao, Ligong
Li, Xuwen
Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title_full Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title_fullStr Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title_full_unstemmed Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title_short Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects()
title_sort marine sponges of the genus stelletta as promising drug sources: chemical and biological aspects()
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437601/
https://www.ncbi.nlm.nih.gov/pubmed/30972275
http://dx.doi.org/10.1016/j.apsb.2018.10.003
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