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Inhibitory effects of thromboxane A(2) generation by ginsenoside Ro due to attenuation of cytosolic phospholipase A(2) phosphorylation and arachidonic acid release

BACKGROUND: Thromboxane A(2) (TXA(2)) induces platelet aggregation and promotes thrombus formation. Although ginsenoside Ro (G-Ro) from Panax ginseng is known to exhibit a Ca(2+)-antagonistic antiplatelet effect, whether it inhibits Ca(2+)-dependent cytosolic phospholipase A(2) (cPLA(2α)) activity t...

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Detalles Bibliográficos
Autores principales:	Shin, Jung-Hae, Kwon, Hyuk-Woo, Rhee, Man Hee, Park, Hwa-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437639/ https://www.ncbi.nlm.nih.gov/pubmed/30976161 http://dx.doi.org/10.1016/j.jgr.2017.12.007

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