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Functional peroxisomes are required for β-cell integrity in mice

OBJECTIVES: Peroxisomes play a crucial role in lipid and reactive oxygen species metabolism, but their importance for pancreatic β-cell functioning is presently unknown. To examine the contribution of peroxisomal metabolism to β-cell homeostasis in mice, we inactivated PEX5, the import receptor for...

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Detalles Bibliográficos
Autores principales:	Baboota, Ritesh Kumar, Shinde, Abhijit Babaji, Lemaire, Katleen, Fransen, Marc, Vinckier, Stefan, Van Veldhoven, Paul P., Schuit, Frans, Baes, Myriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437690/ https://www.ncbi.nlm.nih.gov/pubmed/30795913 http://dx.doi.org/10.1016/j.molmet.2019.02.001

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