Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a multifactorial fatal motoneuron disease without a cure. Ten percent of ALS cases can be pointed to a clear genetic cause, while the remaining 90% is classified as sporadic. Our study was aimed to uncover new connections within the ALS network thro...

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Detalles Bibliográficos
Autores principales: Beltran, S., Nassif, M., Vicencio, E., Arcos, J., Labrador, L., Cortes, B. I., Cortez, C., Bergmann, C. A., Espinoza, S., Hernandez, M. F., Matamala, J. M., Bargsted, L., Matus, S., Rojas-Rivera, D., Bertrand, M. J. M., Medinas, D. B., Hetz, C., Manque, P. A., Woehlbier, U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437924/
https://www.ncbi.nlm.nih.gov/pubmed/30917850
http://dx.doi.org/10.1186/s13024-019-0313-9

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