Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model

BACKGROUND: Aggregation of tau proteins is a distinct hallmark of tauopathies and has been a focus of research and clinical trials for Alzheimer’s Disease. Recent reports have pointed towards a toxic effect of soluble or oligomeric tau in the spreading of tau pathology in Alzheimer’s disease. Here w...

Descripción completa

Detalles Bibliográficos
Autores principales: Green, Claudia, Sydow, Astrid, Vogel, Stefanie, Anglada-Huguet, Marta, Wiedermann, Dirk, Mandelkow, Eckhard, Mandelkow, Eva-Maria, Hoehn, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438042/
https://www.ncbi.nlm.nih.gov/pubmed/30917861
http://dx.doi.org/10.1186/s13024-019-0316-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438042/
https://www.ncbi.nlm.nih.gov/pubmed/30917861
http://dx.doi.org/10.1186/s13024-019-0316-6

Ejemplares similares