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Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer’s disease mouse model
BACKGROUND: Aggregation of tau proteins is a distinct hallmark of tauopathies and has been a focus of research and clinical trials for Alzheimer’s Disease. Recent reports have pointed towards a toxic effect of soluble or oligomeric tau in the spreading of tau pathology in Alzheimer’s disease. Here w...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438042/ https://www.ncbi.nlm.nih.gov/pubmed/30917861 http://dx.doi.org/10.1186/s13024-019-0316-6 |