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Case-control Indian buffet process identifies biomarkers of response to Codrituzumab
BACKGROUND: Codrituzumab, a humanized monoclonal antibody against Glypican-3 (GPC3), which is expressed in hepatocellular carcinoma (HCC), was tested in a randomized phase II trial in advanced HCC patients who had failed prior systemic therapy. Biomarker analysis was performed to identify a responde...
Autores principales: | Pradier, Melanie F., Reis, Bernhard, Jukofsky, Lori, Milletti, Francesca, Ohtomo, Toshihiko, Perez-Cruz, Fernando, Puig, Oscar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438135/ https://www.ncbi.nlm.nih.gov/pubmed/30922327 http://dx.doi.org/10.1186/s12885-019-5472-0 |
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