Natural Killer Cell Degranulation Defect: A Cause for Impaired NK-Cell Cytotoxicity and Hyperinflammation in Fanconi Anemia Patients

Fanconi anemia (FA) is a rare inherited syndrome characterized by progressive bone marrow failure (BMF), abnormal skin pigmentation, short stature, and increased cancer risk. BMF in FA is multifactorial and largely results from the death of hematopoietic stem cells due to genomic instability. Also,...

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Detalles Bibliográficos
Autores principales: Shabrish, Snehal, Kelkar, Madhura, Chavan, Niranjan, Desai, Mukesh, Bargir, Umair, Gupta, Maya, Mehta, Priti, Chichra, Akanksha, S, Chandrakala, Taur, Prasad, Saxena, Vinay, Vundinti, Babu Rao, Madkaikar, Manisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438155/
https://www.ncbi.nlm.nih.gov/pubmed/30949167
http://dx.doi.org/10.3389/fimmu.2019.00490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438155/
https://www.ncbi.nlm.nih.gov/pubmed/30949167
http://dx.doi.org/10.3389/fimmu.2019.00490

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