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Isoforms S and L of MRPL33 from alternative splicing have isoform-specific roles in the chemoresponse to epirubicin in gastric cancer cells via the PI3K/AKT signaling pathway

Drug resistance is a major cause of cancer-associated mortality. Epirubicin-based chemotherapy initially benefits patients with metastatic or advanced gastric cancer; however, tumor recurrence can occur following several courses of treatment. Mitochondrial ribosomal protein L33 (MRPL33)-long (L) and...

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Detalles Bibliográficos
Autores principales: Li, Jie, Feng, Dan, Gao, Cuixia, Zhang, Yingyi, Xu, Jing, Wu, Meihong, Zhan, Xianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438423/
https://www.ncbi.nlm.nih.gov/pubmed/30816492
http://dx.doi.org/10.3892/ijo.2019.4728

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