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α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation

α-hederin, a monodesmosidic triterpenoid saponin, had previously demonstrated strong anticancer effects. In the current study, the pharmacological mechanism of autophagic cell death induced by α-hederin was investigated in human colorectal cancer cells. First, through cell counting kit-8 and colony...

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Detalles Bibliográficos
Autores principales:	Sun, Jian, Feng, Yu, Wang, Yan, Ji, Qing, Cai, Gang, Shi, Lei, Wang, Yiyi, Huang, Yan, Zhang, Jue, Li, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438428/ https://www.ncbi.nlm.nih.gov/pubmed/30896843 http://dx.doi.org/10.3892/ijo.2019.4757

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