Induction and maintenance of bi-functional (IFN-γ (+) IL-2(+) and IL-2(+) TNF-α(+)) T cell responses by DNA prime MVA boosted subtype C prophylactic vaccine tested in a Phase I trial in India

Effective vaccine design relies on accurate knowledge of protection against a pathogen, so as to be able to induce relevant and effective protective responses against it. An ideal Human Immunodeficiency virus (HIV) vaccine should induce humoral as well as cellular immune responses to prevent initial...

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Detalles Bibliográficos
Autores principales: Munusamy Ponnan, Sivasankaran, Pattabiram, Sathyamurthy, Thiruvengadam, Kannan, Goyal, Rajat, Singla, Nikhil, Mukherjee, Joyeeta, Chatrath, Shweta, Bergin, Philip, T. Kopycinski, Jakub, Gilmour, Jill, Kumar, Sriram, Muthu, Malathy, Subramaniam, Sudha, Swaminathan, Soumya, Prasad Tripathy, Srikanth, Luke, Hanna Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438518/
https://www.ncbi.nlm.nih.gov/pubmed/30921340
http://dx.doi.org/10.1371/journal.pone.0213911

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