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Sfrp5 increases glucose-stimulated insulin secretion in the rat pancreatic beta cell line INS-1E

Previous studies reported that secreted frizzled-related protein-5 (Sfrp5) decreases beta cell proliferation and increases fasting insulin levels, but studies on direct effects of Sfrp5 on insulin secretion and its underlying mechanisms are missing. This study examined effects of Sfrp5 on (i) beta c...

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Detalles Bibliográficos
Autores principales:	Carstensen-Kirberg, Maren, Röhrig, Karin, Niersmann, Corinna, Ouwens, D. Margriet, Belgardt, Bengt F., Roden, Michael, Herder, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438539/ https://www.ncbi.nlm.nih.gov/pubmed/30921355 http://dx.doi.org/10.1371/journal.pone.0213650

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