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Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally
DNA and histone modifications exhibit noticeable impacts on gene expression(1). Being the most prevalent internal modification in mRNA, N(6)-Methyladenosine (m(6)A) mRNA modification emerges as an important post-transcriptional mechanism of gene regulation(2-4) and plays critical roles in various no...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438714/ https://www.ncbi.nlm.nih.gov/pubmed/30867593 http://dx.doi.org/10.1038/s41586-019-1016-7 |