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Physicochemical, pharmacokinetics, and histological evaluation of new naproxen-quercetin co-lyophilizate to diminish drug-induced gastric irritations in rats

Quercetin (QUE) is a flavonoid found in several plants and commonly distributed in edible vegetables and fruits. To evaluate the effect of co-lyophilization of naproxen (NPX) with QUE at different weight ratios on physicochemical characteristics induced gastric irritation, and drug pharmacokinetics....

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Detalles Bibliográficos
Autores principales:	Ibrahim, Mohamed Abbas, Shazly, Gamal A., Elossaily, Gehan M., Ezzeldin, Essam, Aleanizy, Fadilah S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438786/ https://www.ncbi.nlm.nih.gov/pubmed/30976186 http://dx.doi.org/10.1016/j.jsps.2019.01.002

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