SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance

Selenoprotein N (SELENON) is an endoplasmic reticulum (ER) protein whose loss of function leads to a congenital myopathy associated with insulin resistance (SEPN1-related myopathy). The exact cause of the insulin resistance in patients with SELENON loss of function is not known. Skeletal muscle is t...

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Detalles Bibliográficos
Autores principales: Varone, Ersilia, Pozzer, Diego, Di Modica, Simona, Chernorudskiy, Alexander, Nogara, Leonardo, Baraldo, Martina, Cinquanta, Mario, Fumagalli, Stefano, Villar-Quiles, Rocio Nur, De Simoni, Maria-Grazia, Blaauw, Bert, Ferreiro, Ana, Zito, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438913/
https://www.ncbi.nlm.nih.gov/pubmed/30921636
http://dx.doi.org/10.1016/j.redox.2019.101176

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