cAMP Stimulates SLC26A3 Activity in Human Colon by a CFTR-Dependent Mechanism That Does Not Require CFTR Activity

BACKGROUND & AIMS: SLC26A3 (DRA) is an electroneutral Cl(-)/HCO(3)(-) exchanger that is present in the apical domain of multiple intestinal segments. An area that has continued to be poorly understood is related to DRA regulation in acute adenosine 3′,5′-cyclic monophosphate (cAMP)-related diarr...

Descripción completa

Detalles Bibliográficos
Autores principales: Tse, Chung-Ming, Yin, Jianyi, Singh, Varsha, Sarker, Rafiquel, Lin, Ruxian, Verkman, Alan S., Turner, Jerrold R., Donowitz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438990/
https://www.ncbi.nlm.nih.gov/pubmed/30659943
http://dx.doi.org/10.1016/j.jcmgh.2019.01.002

Ejemplares similares

Ejemplares similares