Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers

Mutations in progranulin (GRN) cause heterogeneous clinical syndromes, including behavioral variant frontotemporal dementia (bvFTD), primary progressive aphasia (PPA), corticobasal syndrome (CBS) and Alzheimer-type dementia (AD-type dementia). Human studies have shown that presymptomatic GRN carrier...

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Detalles Bibliográficos
Autores principales: Lee, Suzee E., Sias, Ana C., Kosik, Eena L., Flagan, Taru M., Deng, Jersey, Chu, Stephanie A., Brown, Jesse A., Vidovszky, Anna A., Ramos, Eliana Marisa, Gorno-Tempini, Maria Luisa, Karydas, Anna M., Coppola, Giovanni, Geschwind, Daniel H., Rademakers, Rosa, Boeve, Bradley F., Boxer, Adam L., Rosen, Howard J., Miller, Bruce L., Seeley, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438992/
https://www.ncbi.nlm.nih.gov/pubmed/30921613
http://dx.doi.org/10.1016/j.nicl.2019.101751

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