A randomised, investigator-initiated, clinical trial of the effects of fentanyl on P2Y12-receptor inhibition in patients with ST-elevation myocardial infarction who are pre-treated with crushed ticagrelor: rationale and design of the Opioids aNd crushed Ticagrelor In Myocardial infarction Evaluation (ON-TIME 3) trial

BACKGROUND: Fast and accurate platelet inhibition is an important therapeutic goal in the acute treatment of patients with ST-elevation myocardial infarction (STEMI). Platelet inhibitory effects induced by oral P2Y12-receptor antagonists are delayed in STEMI patients undergoing primary percutaneous...

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Detalles Bibliográficos
Autores principales: Tavenier, A. H., Hermanides, R. S., Ottervanger, J. P., Rasoul, S., Slingerland, R. J., Tolsma, R., van Workum, S., Kedhi, E., van ’t Hof, A. W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bohn Stafleu van Loghum 2019
Materias:
Original Article – Design Study Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439041/
https://www.ncbi.nlm.nih.gov/pubmed/30767166
http://dx.doi.org/10.1007/s12471-019-1241-6

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