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Integrin-independent support of cancer drug resistance by tetraspanin CD151
Tetraspanin protein CD151 has typically been studied as binding partner and functional regulator of laminin-binding integrins. However, we show here that CD151 supports anti-cancer drug resistance independent of integrins. CD151 ablation sensitized multiple tumor cell types to several anti-cancer dr...
Autores principales: | Hwang, Soonyean, Takimoto, Takayuki, Hemler, Martin E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439156/ https://www.ncbi.nlm.nih.gov/pubmed/30778617 http://dx.doi.org/10.1007/s00018-019-03014-7 |
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