(1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)

CD44 is a universally and abundantly expressed single-pass type I protein that spans the cytoplasmic membrane and is considered the principal receptor for hyaluronan in the extracellular matrix. CD44 exerts a multitude of biological functions, especially in cell adhesion and migration, and its dereg...

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Autores principales: Frühbauer, Benjamin, Mateos, Borja, Konrat, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439174/
https://www.ncbi.nlm.nih.gov/pubmed/30474821
http://dx.doi.org/10.1007/s12104-018-9861-0
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author Frühbauer, Benjamin
Mateos, Borja
Konrat, Robert
author_facet Frühbauer, Benjamin
Mateos, Borja
Konrat, Robert
author_sort Frühbauer, Benjamin
collection PubMed
description CD44 is a universally and abundantly expressed single-pass type I protein that spans the cytoplasmic membrane and is considered the principal receptor for hyaluronan in the extracellular matrix. CD44 exerts a multitude of biological functions, especially in cell adhesion and migration, and its deregulation has several pathological implications, including a putative role in cancer cell dissemination. Here we report the NMR chemical shift assignment of the recombinant intrinsically disordered CD44 cytoplasmic region (669–742).
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spelling pubmed-64391742019-04-15 (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742) Frühbauer, Benjamin Mateos, Borja Konrat, Robert Biomol NMR Assign Article CD44 is a universally and abundantly expressed single-pass type I protein that spans the cytoplasmic membrane and is considered the principal receptor for hyaluronan in the extracellular matrix. CD44 exerts a multitude of biological functions, especially in cell adhesion and migration, and its deregulation has several pathological implications, including a putative role in cancer cell dissemination. Here we report the NMR chemical shift assignment of the recombinant intrinsically disordered CD44 cytoplasmic region (669–742). Springer Netherlands 2018-11-24 2019 /pmc/articles/PMC6439174/ /pubmed/30474821 http://dx.doi.org/10.1007/s12104-018-9861-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Frühbauer, Benjamin
Mateos, Borja
Konrat, Robert
(1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title_full (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title_fullStr (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title_full_unstemmed (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title_short (1)H, (15)N, (13)C resonance assignment of the human CD44 cytoplasmic tail (669–742)
title_sort (1)h, (15)n, (13)c resonance assignment of the human cd44 cytoplasmic tail (669–742)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439174/
https://www.ncbi.nlm.nih.gov/pubmed/30474821
http://dx.doi.org/10.1007/s12104-018-9861-0
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AT konratrobert 1h15n13cresonanceassignmentofthehumancd44cytoplasmictail669742

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