Nkx-2.5 Regulates MDR1 Expression via Its Upstream Promoter in Breast Cancer Cells

BACKGROUND: Increased expression of MDR1 gene is one of the major mechanisms responsible for multidrug resistance in cancer cells. Two alternative promoters, upstream and downstream, are responsible for transcription of MDR1 gene in the human. However, the molecular mechanism regarding the transacti...

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Detalles Bibliográficos
Autores principales: Lim, Jung-Suk, Jung, Gyu Yeon, Park, Seung-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439202/
https://www.ncbi.nlm.nih.gov/pubmed/30940996
http://dx.doi.org/10.3346/jkms.2019.34.e100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439202/
https://www.ncbi.nlm.nih.gov/pubmed/30940996
http://dx.doi.org/10.3346/jkms.2019.34.e100

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