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Lack of IκBNS promotes cholate-containing high-fat diet-induced inflammation and atherogenesis in low-density lipoprotein (LDL) receptor-deficient mice
BACKGROUND: IκBNS, a nuclear IκB protein, regulates a subset of Toll-like receptor (TLR) dependent genes. A cholate-containing high-fat diet (HFD(CA(+))) induces TLR4 mediated early inflammatory response. The present study aims to clarify that the lack of IκBNS promotes atherogenesis in low-density...
Autores principales: | Kitamura, Kenichi, Isoda, Kikuo, Akita, Koji, Miyosawa, Katsutoshi, Kadoguchi, Tomoyasu, Shimada, Kazunori, Daida, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439265/ https://www.ncbi.nlm.nih.gov/pubmed/30976650 http://dx.doi.org/10.1016/j.ijcha.2019.03.004 |
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