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Type I interferon protects neurons from prions in in vivo models
Infectious prions comprising abnormal prion protein, which is produced by structural conversion of normal prion protein, are responsible for transmissible spongiform encephalopathies including Creutzfeldt-Jakob disease in humans. Prions are infectious agents that do not possess a genome and the path...
Autores principales: | Ishibashi, Daisuke, Homma, Takujiro, Nakagaki, Takehiro, Fuse, Takayuki, Sano, Kazunori, Satoh, Katsuya, Mori, Tsuyoshi, Atarashi, Ryuichiro, Nishida, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439327/ https://www.ncbi.nlm.nih.gov/pubmed/30753318 http://dx.doi.org/10.1093/brain/awz016 |
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