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Circulating Tumor DNA Detection in the Management of Anti-EGFR Therapy for Advanced Colorectal Cancer
Background: Anti-EGFR antibodies are a standard care for advanced KRAS-wild type colorectal cancers. Circulating tumor DNA (ctDNA) monitoring during therapy can detect emergence of KRAS mutant clones and early resistance to therapy. Case Presentation: We describe a 61-years-old man presenting a meta...
Autores principales: | Knebel, Franciele H., Bettoni, Fabiana, da Fonseca, Leonardo G., Camargo, Anamaria A., Sabbaga, Jorge, Jardim, Denis L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439419/ https://www.ncbi.nlm.nih.gov/pubmed/30967998 http://dx.doi.org/10.3389/fonc.2019.00170 |
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