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Deep learning opens new horizons in personalized medicine

Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management...

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Autores principales: Papadakis, Georgios Z., Karantanas, Apostolos H., Tsiknakis, Manolis, Tsatsakis, Aristidis, Spandidos, Demetrios A., Marias, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439426/
https://www.ncbi.nlm.nih.gov/pubmed/30988951
http://dx.doi.org/10.3892/br.2019.1199
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author Papadakis, Georgios Z.
Karantanas, Apostolos H.
Tsiknakis, Manolis
Tsatsakis, Aristidis
Spandidos, Demetrios A.
Marias, Kostas
author_facet Papadakis, Georgios Z.
Karantanas, Apostolos H.
Tsiknakis, Manolis
Tsatsakis, Aristidis
Spandidos, Demetrios A.
Marias, Kostas
author_sort Papadakis, Georgios Z.
collection PubMed
description Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management. Facilitating personalized / precision medicine requires taking into account multiple heterogenous parameters, such as sociodemographics, gene variability, environmental and lifestyle factors. Therefore, one of the most critical challenges in personalized medicine is the need to transform large, multi-modal data into decision support tools, capable of bridging the translational gap to the clinical setting. Towards these challenges, deep learning (DL) provides a novel approach, which enables obtaining or developing high-accuracy, multi-modal predictive models, that allow the implementation of the personalized medicine vision in the near future. DL is a highly effective strategy in addressing these challenges, with DL-based models leading to unprecedented results, matching or even improving state-of-the-art prediction/detection rates based on both intuitive and non-intuitive disease descriptors. These results hold promise for significant socio-economic benefits from the application of DL personalized medicine.
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spelling pubmed-64394262019-04-15 Deep learning opens new horizons in personalized medicine Papadakis, Georgios Z. Karantanas, Apostolos H. Tsiknakis, Manolis Tsatsakis, Aristidis Spandidos, Demetrios A. Marias, Kostas Biomed Rep Review Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management. Facilitating personalized / precision medicine requires taking into account multiple heterogenous parameters, such as sociodemographics, gene variability, environmental and lifestyle factors. Therefore, one of the most critical challenges in personalized medicine is the need to transform large, multi-modal data into decision support tools, capable of bridging the translational gap to the clinical setting. Towards these challenges, deep learning (DL) provides a novel approach, which enables obtaining or developing high-accuracy, multi-modal predictive models, that allow the implementation of the personalized medicine vision in the near future. DL is a highly effective strategy in addressing these challenges, with DL-based models leading to unprecedented results, matching or even improving state-of-the-art prediction/detection rates based on both intuitive and non-intuitive disease descriptors. These results hold promise for significant socio-economic benefits from the application of DL personalized medicine. D.A. Spandidos 2019-04 2019-03-13 /pmc/articles/PMC6439426/ /pubmed/30988951 http://dx.doi.org/10.3892/br.2019.1199 Text en Copyright: © Georgios Z. Papadakis et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Review
Papadakis, Georgios Z.
Karantanas, Apostolos H.
Tsiknakis, Manolis
Tsatsakis, Aristidis
Spandidos, Demetrios A.
Marias, Kostas
Deep learning opens new horizons in personalized medicine
title Deep learning opens new horizons in personalized medicine
title_full Deep learning opens new horizons in personalized medicine
title_fullStr Deep learning opens new horizons in personalized medicine
title_full_unstemmed Deep learning opens new horizons in personalized medicine
title_short Deep learning opens new horizons in personalized medicine
title_sort deep learning opens new horizons in personalized medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439426/
https://www.ncbi.nlm.nih.gov/pubmed/30988951
http://dx.doi.org/10.3892/br.2019.1199
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