Cargando…
Deep learning opens new horizons in personalized medicine
Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439426/ https://www.ncbi.nlm.nih.gov/pubmed/30988951 http://dx.doi.org/10.3892/br.2019.1199 |
_version_ | 1783407262633558016 |
---|---|
author | Papadakis, Georgios Z. Karantanas, Apostolos H. Tsiknakis, Manolis Tsatsakis, Aristidis Spandidos, Demetrios A. Marias, Kostas |
author_facet | Papadakis, Georgios Z. Karantanas, Apostolos H. Tsiknakis, Manolis Tsatsakis, Aristidis Spandidos, Demetrios A. Marias, Kostas |
author_sort | Papadakis, Georgios Z. |
collection | PubMed |
description | Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management. Facilitating personalized / precision medicine requires taking into account multiple heterogenous parameters, such as sociodemographics, gene variability, environmental and lifestyle factors. Therefore, one of the most critical challenges in personalized medicine is the need to transform large, multi-modal data into decision support tools, capable of bridging the translational gap to the clinical setting. Towards these challenges, deep learning (DL) provides a novel approach, which enables obtaining or developing high-accuracy, multi-modal predictive models, that allow the implementation of the personalized medicine vision in the near future. DL is a highly effective strategy in addressing these challenges, with DL-based models leading to unprecedented results, matching or even improving state-of-the-art prediction/detection rates based on both intuitive and non-intuitive disease descriptors. These results hold promise for significant socio-economic benefits from the application of DL personalized medicine. |
format | Online Article Text |
id | pubmed-6439426 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-64394262019-04-15 Deep learning opens new horizons in personalized medicine Papadakis, Georgios Z. Karantanas, Apostolos H. Tsiknakis, Manolis Tsatsakis, Aristidis Spandidos, Demetrios A. Marias, Kostas Biomed Rep Review Although the idea of the personalization of patient care dates back to the time of Hippocrates, recent advances in diagnostic medical imaging and molecular medicine are gradually transforming healthcare services, by offering information and diagnostic tools enabling individualized patient management. Facilitating personalized / precision medicine requires taking into account multiple heterogenous parameters, such as sociodemographics, gene variability, environmental and lifestyle factors. Therefore, one of the most critical challenges in personalized medicine is the need to transform large, multi-modal data into decision support tools, capable of bridging the translational gap to the clinical setting. Towards these challenges, deep learning (DL) provides a novel approach, which enables obtaining or developing high-accuracy, multi-modal predictive models, that allow the implementation of the personalized medicine vision in the near future. DL is a highly effective strategy in addressing these challenges, with DL-based models leading to unprecedented results, matching or even improving state-of-the-art prediction/detection rates based on both intuitive and non-intuitive disease descriptors. These results hold promise for significant socio-economic benefits from the application of DL personalized medicine. D.A. Spandidos 2019-04 2019-03-13 /pmc/articles/PMC6439426/ /pubmed/30988951 http://dx.doi.org/10.3892/br.2019.1199 Text en Copyright: © Georgios Z. Papadakis et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Review Papadakis, Georgios Z. Karantanas, Apostolos H. Tsiknakis, Manolis Tsatsakis, Aristidis Spandidos, Demetrios A. Marias, Kostas Deep learning opens new horizons in personalized medicine |
title | Deep learning opens new horizons in personalized medicine |
title_full | Deep learning opens new horizons in personalized medicine |
title_fullStr | Deep learning opens new horizons in personalized medicine |
title_full_unstemmed | Deep learning opens new horizons in personalized medicine |
title_short | Deep learning opens new horizons in personalized medicine |
title_sort | deep learning opens new horizons in personalized medicine |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439426/ https://www.ncbi.nlm.nih.gov/pubmed/30988951 http://dx.doi.org/10.3892/br.2019.1199 |
work_keys_str_mv | AT papadakisgeorgiosz deeplearningopensnewhorizonsinpersonalizedmedicine AT karantanasapostolosh deeplearningopensnewhorizonsinpersonalizedmedicine AT tsiknakismanolis deeplearningopensnewhorizonsinpersonalizedmedicine AT tsatsakisaristidis deeplearningopensnewhorizonsinpersonalizedmedicine AT spandidosdemetriosa deeplearningopensnewhorizonsinpersonalizedmedicine AT mariaskostas deeplearningopensnewhorizonsinpersonalizedmedicine |