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Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p

UDP-glucuronosyltransferase (UGT) 2A1 is an important enzyme in the detoxification of polycyclic aromatic hydrocarbons found in cigarette smoke. This enzyme is expressed in aerodigestive tract tissues including lung as both its wild-type and exon 4-deleted splice variant isoforms, with the latter ac...

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Detalles Bibliográficos
Autores principales:	Sutliff, Aimee K., Watson, Christy J. W., Chen, Gang, Lazarus, Philip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Pharmacology and Experimental Therapeutics 2019
Materias:	Metabolism, Transport, and Pharmacogenomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439457/ https://www.ncbi.nlm.nih.gov/pubmed/30850392 http://dx.doi.org/10.1124/jpet.118.255935

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