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Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

BACKGROUND: A male gender driven obesity paradox (improved survival for overweight/obese patients compared to normal weight) was recently shown in melanoma in the context of checkpoint inhibition (anti-PD-1/anti-CTLA4 monotherapy) in a pooled meta-analysis. We characterized the relationship of Body...

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Detalles Bibliográficos
Autores principales: Naik, Girish S., Waikar, Sushrut S., Johnson, Alistair E. W., Buchbinder, Elizabeth I., Haq, Rizwan, Hodi, F. Stephen, Schoenfeld, Jonathan D., Ott, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440018/
https://www.ncbi.nlm.nih.gov/pubmed/30922394
http://dx.doi.org/10.1186/s40425-019-0512-5