Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

TAR DNA-binding protein (TDP-43) is a ubiquitously expressed nuclear protein, which participates in a number of cellular processes and has been identified as the major pathological factor in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). Here we constructed a condi...

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Detalles Bibliográficos
Autores principales: Wu, Lien-Szu, Cheng, Wei-Cheng, Chen, Chia-Ying, Wu, Ming-Che, Wang, Yi-Chi, Tseng, Yu-Hsiang, Chuang, Trees-Juen, Shen, C.-K. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440020/
https://www.ncbi.nlm.nih.gov/pubmed/30922385
http://dx.doi.org/10.1186/s40478-019-0674-x

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