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Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension

Pulmonary hypertension (PH), a heterogeneous vascular disease, consists of subtypes with overlapping clinical phenotypes. MicroRNAs, small non-coding RNAs that negatively regulate gene expression, have emerged as regulators of PH pathogenesis. The muscle-specific micro RNA (miR)-204 is known to be d...

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Detalles Bibliográficos
Autores principales: Estephan, Leonard E., Genuardi, Michael V., Kosanovich, Chad M., Risbano, Michael G., Zhang, Yingze, Petro, Nancy, Watson, Annie, Al Aaraj, Yassmin, Sembrat, John C., Rojas, Mauricio, Goncharov, Dmitry A., Simon, Marc A., Goncharova, Elena A., Vaidya, Anjali, Smith, Akaya, Mazurek, Jeremy, Han, Yuchi, Chan, Stephen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440051/
https://www.ncbi.nlm.nih.gov/pubmed/30854934
http://dx.doi.org/10.1177/2045894019840646