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Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes

BACKGROUND: Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been explored, and the efficacy of MSCs started to be deci...

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Detalles Bibliográficos
Autores principales: Ragni, Enrico, Perucca Orfei, Carlotta, De Luca, Paola, Lugano, Gaia, Viganò, Marco, Colombini, Alessandra, Valli, Federico, Zacchetti, Daniele, Bollati, Valentina, de Girolamo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440078/
https://www.ncbi.nlm.nih.gov/pubmed/30922413
http://dx.doi.org/10.1186/s13287-019-1215-z