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Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes
BACKGROUND: Osteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been explored, and the efficacy of MSCs started to be deci...
Autores principales: | Ragni, Enrico, Perucca Orfei, Carlotta, De Luca, Paola, Lugano, Gaia, Viganò, Marco, Colombini, Alessandra, Valli, Federico, Zacchetti, Daniele, Bollati, Valentina, de Girolamo, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440078/ https://www.ncbi.nlm.nih.gov/pubmed/30922413 http://dx.doi.org/10.1186/s13287-019-1215-z |
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