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Increased expression of cancer-associated fibroblast markers at the invasive front and its association with tumor-stroma ratio in colorectal cancer

BACKGROUND: The tumor microenvironment has a critical role in regulating cancer cell behavior. Tumors with high stromal content are associated with poor patient outcome. The tumor-stroma ratio (TSR) identifies colorectal cancers (CRC) with poor patient prognosis based on hematoxylin & eosin stai...

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Detalles Bibliográficos
Autores principales:	Sandberg, Tessa P., Stuart, Maaike P. M. E., Oosting, Jan, Tollenaar, Rob A. E. M., Sier, Cornelis F. M., Mesker, Wilma E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440123/ https://www.ncbi.nlm.nih.gov/pubmed/30922247 http://dx.doi.org/10.1186/s12885-019-5462-2

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