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Molecular basis of the anti-hyperglycemic activity of RA-3 in hyperlipidemic and streptozotocin-induced type 2 diabetes in rats
BACKGROUND: Insulin resistance is a hallmark of type 2 diabetes mellitus (T2DM) and the underlying cause of various metabolic changes observed in type 2 diabetic patients. This study investigated the molecular basis of the anti-hyperglycemic activity of the lanosteryl triterpene (RA-3), from Protorh...
Autores principales: | Mabhida, Sihle Ephraim, Johnson, Rabia, Ndlovu, Musawenkosi, Louw, Johan, Opoku, Andrew, Mosa, Rebamang Anthony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440151/ https://www.ncbi.nlm.nih.gov/pubmed/30976328 http://dx.doi.org/10.1186/s13098-019-0424-z |
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