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Identification of trans-eQTLs using mediation analysis with multiple mediators

BACKGROUND: Mapping expression quantitative trait loci (eQTLs) has provided insight into gene regulation. Compared to cis-eQTLs, the regulatory mechanisms of trans-eQTLs are less known. Previous studies suggest that trans-eQTLs may regulate expression of remote genes by altering the expression of ne...

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Detalles Bibliográficos
Autores principales:	Shan, Nayang, Wang, Zuoheng, Hou, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440281/ https://www.ncbi.nlm.nih.gov/pubmed/30925861 http://dx.doi.org/10.1186/s12859-019-2651-6

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