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Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response
PURPOSE: Melanoma is the most aggressive form of skin cancer. Chemotherapy at a late stage fails due to low accumulation in tumors, indicating the need for targeted therapy. MATERIALS AND METHODS: To increase drug uptake by tumor cells, we have targeted doxorubicin-containing liposomes using a T-cel...
Autores principales: | Saeed, Mesha, Zalba, Sara, Seynhaeve, Ann L B, Debets, Reno, ten Hagen, Timo L M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440454/ https://www.ncbi.nlm.nih.gov/pubmed/30988609 http://dx.doi.org/10.2147/IJN.S190736 |
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