Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome

There remains a pressing need for biomarkers that can predict who will progress to active tuberculosis (TB) after exposure to Mycobacterium tuberculosis (MTB) bacterium. By analyzing cohorts of household contacts of TB index cases (HHCs) and a stringent non-human primate (NHP) challenge model, we ev...

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Detalles Bibliográficos
Autores principales: Duffy, Fergal J., Weiner, January, Hansen, Scott, Tabb, David L., Suliman, Sara, Thompson, Ethan, Maertzdorf, Jeroen, Shankar, Smitha, Tromp, Gerard, Parida, Shreemanta, Dover, Drew, Axthelm, Michael K., Sutherland, Jayne S., Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Picker, Louis J., Walzl, Gerhard, Kaufmann, Stefan H. E., Zak, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440524/
https://www.ncbi.nlm.nih.gov/pubmed/30967866
http://dx.doi.org/10.3389/fimmu.2019.00527

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