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Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare tumours. We describe a CAPNON in the posterior fossa and its associated neuropsychological sequelae to provide further evidence for the role of cerebellum in cognitive function. We report the clinical details, imaging, pre-operative neurop...

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Autores principales: Thakur, Bhaskar, Riches, Simon, Costello, Angela, Aizpurua, Miren, Bodi, Istvan, Ashkan, Keyoumars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440558/
https://www.ncbi.nlm.nih.gov/pubmed/30967982
http://dx.doi.org/10.7759/cureus.3982
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author Thakur, Bhaskar
Riches, Simon
Costello, Angela
Aizpurua, Miren
Bodi, Istvan
Ashkan, Keyoumars
author_facet Thakur, Bhaskar
Riches, Simon
Costello, Angela
Aizpurua, Miren
Bodi, Istvan
Ashkan, Keyoumars
author_sort Thakur, Bhaskar
collection PubMed
description Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare tumours. We describe a CAPNON in the posterior fossa and its associated neuropsychological sequelae to provide further evidence for the role of cerebellum in cognitive function. We report the clinical details, imaging, pre-operative neuropsychological assessment, histological features and management of a patient with such a tumour in the posterior fossa location. Detailed pre-operative neuropsychological assessment identified a number of cognitive deficits that had the hallmarks of dysexecutive syndrome. Post-surgery, there was considerable improvement, most notably on processing speed tasks and selected executive tests. This rare case provides further evidence for the role of cerebellum in cognitive function.
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spelling pubmed-64405582019-04-09 Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More Thakur, Bhaskar Riches, Simon Costello, Angela Aizpurua, Miren Bodi, Istvan Ashkan, Keyoumars Cureus Pathology Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare tumours. We describe a CAPNON in the posterior fossa and its associated neuropsychological sequelae to provide further evidence for the role of cerebellum in cognitive function. We report the clinical details, imaging, pre-operative neuropsychological assessment, histological features and management of a patient with such a tumour in the posterior fossa location. Detailed pre-operative neuropsychological assessment identified a number of cognitive deficits that had the hallmarks of dysexecutive syndrome. Post-surgery, there was considerable improvement, most notably on processing speed tasks and selected executive tests. This rare case provides further evidence for the role of cerebellum in cognitive function. Cureus 2019-01-29 /pmc/articles/PMC6440558/ /pubmed/30967982 http://dx.doi.org/10.7759/cureus.3982 Text en Copyright © 2019, Thakur et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Thakur, Bhaskar
Riches, Simon
Costello, Angela
Aizpurua, Miren
Bodi, Istvan
Ashkan, Keyoumars
Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title_full Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title_fullStr Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title_full_unstemmed Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title_short Calcifying Pseudoneoplasm of the Neuraxis, Cerebellum and Cognition: A Rare Opportunity to Learn More
title_sort calcifying pseudoneoplasm of the neuraxis, cerebellum and cognition: a rare opportunity to learn more
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440558/
https://www.ncbi.nlm.nih.gov/pubmed/30967982
http://dx.doi.org/10.7759/cureus.3982
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