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Influenza A(H3N2) virus exhibiting reduced susceptibility to baloxavir due to a polymerase acidic subunit I38T substitution detected from a hospitalised child without prior baloxavir treatment, Japan, January 2019

In January 2019, two influenza A(H3N2) viruses carrying an I38T substitution in the polymerase acidic subunit (PA), which confers reduced susceptibility to baloxavir, were detected from epidemiologically unrelated hospitalised children in Japan. The viruses exhibited reduced susceptibility to baloxa...

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Detalles Bibliográficos
Autores principales: Takashita, Emi, Kawakami, Chiharu, Ogawa, Rie, Morita, Hiroko, Fujisaki, Seiichiro, Shirakura, Masayuki, Miura, Hideka, Nakamura, Kazuya, Kishida, Noriko, Kuwahara, Tomoko, Ota, Akira, Togashi, Hayato, Saito, Ayako, Mitamura, Keiko, Abe, Takashi, Ichikawa, Masataka, Yamazaki, Masahiko, Watanabe, Shinji, Odagiri, Takato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440584/
https://www.ncbi.nlm.nih.gov/pubmed/30914078
http://dx.doi.org/10.2807/1560-7917.ES.2019.24.12.1900170