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Systemic pharmacokinetic/pharmacodynamic analysis of intravitreal aflibercept injection in patients with retinal diseases

OBJECTIVE: Explore relationships between systemic exposure to intravitreal aflibercept injection (IAI) and systemic pharmacodynamic effects via post hoc analyses of clinical trials of IAI for neovascular age-related macular degeneration (nAMD) or diabetic macular oedema (DME). METHODS AND ANALYSIS:...

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Detalles Bibliográficos
Autores principales: Kaiser, Peter K, Kodjikian, Laurent, Korobelnik, Jean-Francois, Winkler, Julia, Torri, Albert, Zeitz, Oliver, Vitti, Robert, Ahlers, Cristiane, Zimmermann, Torsten, Dicioccio, A Thomas, Höchel, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440611/
https://www.ncbi.nlm.nih.gov/pubmed/30997397
http://dx.doi.org/10.1136/bmjophth-2018-000185