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Systemic pharmacokinetic/pharmacodynamic analysis of intravitreal aflibercept injection in patients with retinal diseases

OBJECTIVE: Explore relationships between systemic exposure to intravitreal aflibercept injection (IAI) and systemic pharmacodynamic effects via post hoc analyses of clinical trials of IAI for neovascular age-related macular degeneration (nAMD) or diabetic macular oedema (DME). METHODS AND ANALYSIS:...

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Detalles Bibliográficos
Autores principales:	Kaiser, Peter K, Kodjikian, Laurent, Korobelnik, Jean-Francois, Winkler, Julia, Torri, Albert, Zeitz, Oliver, Vitti, Robert, Ahlers, Cristiane, Zimmermann, Torsten, Dicioccio, A Thomas, Höchel, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440611/ https://www.ncbi.nlm.nih.gov/pubmed/30997397 http://dx.doi.org/10.1136/bmjophth-2018-000185

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