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Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study
The clinical, virologic, and immunologic findings in a female Ebola virus disease patient are described. During the long-term follow-up, Ebola virus RNA was detectable in vaginal fluid before 36 days after symptom onset, with nearly an identical genome sequence as in acute phase blood. Ebola-specifi...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440679/ https://www.ncbi.nlm.nih.gov/pubmed/30949523 http://dx.doi.org/10.1093/ofid/ofz068 |
| _version_ | 1783407434762551296 |
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| author | Liu, William J Sesay, Foday R Coursier, Antoine Knust, Barbara Marrinan, Jaclyn E Whitmer, Shannon McDonald, Suzanna L R Gaillard, Philippe Liu, Yang Su, Qiudong Zhang, Yong Crozier, Ian Ariyarajah, Archchun Carino, Marylin Massaquoi, Thomas Broutet, Nathalie Xu, Wenbo Wu, Guizhen Ströher, Ute Gao, George F Formenty, Pierre Sahr, Foday Deen, Gibrilla F |
| author_facet | Liu, William J Sesay, Foday R Coursier, Antoine Knust, Barbara Marrinan, Jaclyn E Whitmer, Shannon McDonald, Suzanna L R Gaillard, Philippe Liu, Yang Su, Qiudong Zhang, Yong Crozier, Ian Ariyarajah, Archchun Carino, Marylin Massaquoi, Thomas Broutet, Nathalie Xu, Wenbo Wu, Guizhen Ströher, Ute Gao, George F Formenty, Pierre Sahr, Foday Deen, Gibrilla F |
| author_sort | Liu, William J |
| collection | PubMed |
| description | The clinical, virologic, and immunologic findings in a female Ebola virus disease patient are described. During the long-term follow-up, Ebola virus RNA was detectable in vaginal fluid before 36 days after symptom onset, with nearly an identical genome sequence as in acute phase blood. Ebola-specific T cells retained activation at 56 days after disease onset. |
| format | Online Article Text |
| id | pubmed-6440679 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-64406792019-04-04 Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study Liu, William J Sesay, Foday R Coursier, Antoine Knust, Barbara Marrinan, Jaclyn E Whitmer, Shannon McDonald, Suzanna L R Gaillard, Philippe Liu, Yang Su, Qiudong Zhang, Yong Crozier, Ian Ariyarajah, Archchun Carino, Marylin Massaquoi, Thomas Broutet, Nathalie Xu, Wenbo Wu, Guizhen Ströher, Ute Gao, George F Formenty, Pierre Sahr, Foday Deen, Gibrilla F Open Forum Infect Dis Brief Report The clinical, virologic, and immunologic findings in a female Ebola virus disease patient are described. During the long-term follow-up, Ebola virus RNA was detectable in vaginal fluid before 36 days after symptom onset, with nearly an identical genome sequence as in acute phase blood. Ebola-specific T cells retained activation at 56 days after disease onset. Oxford University Press 2019-02-26 /pmc/articles/PMC6440679/ /pubmed/30949523 http://dx.doi.org/10.1093/ofid/ofz068 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Brief Report Liu, William J Sesay, Foday R Coursier, Antoine Knust, Barbara Marrinan, Jaclyn E Whitmer, Shannon McDonald, Suzanna L R Gaillard, Philippe Liu, Yang Su, Qiudong Zhang, Yong Crozier, Ian Ariyarajah, Archchun Carino, Marylin Massaquoi, Thomas Broutet, Nathalie Xu, Wenbo Wu, Guizhen Ströher, Ute Gao, George F Formenty, Pierre Sahr, Foday Deen, Gibrilla F Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title | Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title_full | Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title_fullStr | Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title_full_unstemmed | Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title_short | Comprehensive Clinical and Laboratory Follow-up of a Female Patient With Ebola Virus Disease: Sierra Leone Ebola Virus Persistence Study |
| title_sort | comprehensive clinical and laboratory follow-up of a female patient with ebola virus disease: sierra leone ebola virus persistence study |
| topic | Brief Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440679/ https://www.ncbi.nlm.nih.gov/pubmed/30949523 http://dx.doi.org/10.1093/ofid/ofz068 |
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