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Hypoxia‐inducible factor‐1 α deletion in myeloid lineage attenuates hypoxia‐induced pulmonary hypertension

Hypoxemia is seen in patients with pulmonary hypertension and hypoxic pulmonary vasoconstriction worsens their clinical condition. However, vasoconstriction is not the only aspect through which hypoxia induces the progression to pulmonary hypertension. Hypoxia‐inducible factor‐1α (HIF‐1α) is a trans...

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Detalles Bibliográficos
Autores principales: Kojima, Hiroshi, Tokunou, Tomotake, Takahara, Yusuke, Sunagawa, Kenji, Hirooka, Yoshitaka, Ichiki, Toshihiro, Tsutsui, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440913/
https://www.ncbi.nlm.nih.gov/pubmed/30927327
http://dx.doi.org/10.14814/phy2.14025

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