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Metformin induces the AP-1 transcription factor network in normal dermal fibroblasts

Metformin is a widely-used treatment for type 2 diabetes and is reported to extend health and lifespan as a caloric restriction (CR) mimetic. Although the benefits of metformin are well documented, the impact of this compound on the function and organization of the genome in normal tissues is unclea...

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Detalles Bibliográficos
Autores principales:	Gillespie, Zoe E., Wang, Chenxuan, Vadan, Flaviu, Yu, Topaza Y., Ausió, Juan, Kusalik, Anthony, Eskiw, Christopher H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441003/ https://www.ncbi.nlm.nih.gov/pubmed/30926854 http://dx.doi.org/10.1038/s41598-019-41839-1

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