Specialized dendritic cells induce tumor-promoting IL-10(+)IL-17(+) FoxP3(neg) regulatory CD4(+) T cells in pancreatic carcinoma

The drivers and the specification of CD4(+) T cell differentiation in the tumor microenvironment and their contributions to tumor immunity or tolerance are incompletely understood. Using models of pancreatic ductal adenocarcinoma (PDA), we show that a distinct subset of tumor-infiltrating dendritic...

Descripción completa

Detalles Bibliográficos
Autores principales: Barilla, Rocky M., Diskin, Brian, Caso, Raul Caso, Lee, Ki Buom, Mohan, Navyatha, Buttar, Chandan, Adam, Salma, Sekendiz, Zennur, Wang, Junjie, Salas, Ruben D., Cassini, Marcelo F., Karlen, Jason, Sundberg, Belen, Akbar, Hashem, Levchenko, Dmitry, Gakhal, Inderdeep, Gutierrez, Johana, Wang, Wei, Hundeyin, Mautin, Torres-Hernandez, Alejandro, Leinwand, Joshua, Kurz, Emma, Rossi, Juan A. Kochen, Mishra, Ankita, Liria, Miguel, Sanchez, Gustavo, Panta, Jyoti, Loke, P’ng, Aykut, Berk, Miller, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441038/
https://www.ncbi.nlm.nih.gov/pubmed/30926808
http://dx.doi.org/10.1038/s41467-019-09416-2

Ejemplares similares

Ejemplares similares