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Multiplex imaging relates quantal glutamate release to presynaptic Ca(2+) homeostasis at multiple synapses in situ
Information processing by brain circuits depends on Ca(2+)-dependent, stochastic release of the excitatory neurotransmitter glutamate. Whilst optical glutamate sensors have enabled detection of synaptic discharges, understanding presynaptic machinery requires simultaneous readout of glutamate releas...
Autores principales: | Jensen, Thomas P., Zheng, Kaiyu, Cole, Nicholas, Marvin, Jonathan S., Looger, Loren L., Rusakov, Dmitri A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441074/ https://www.ncbi.nlm.nih.gov/pubmed/30926781 http://dx.doi.org/10.1038/s41467-019-09216-8 |
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