Investigating the effects of Pirfenidone on TGF-β1 stimulated non-SMAD signaling pathways in Dupuytren’s disease -derived fibroblasts

BACKGROUND: Dupuytren’s disease (DD) is a progressive, debilitating condition of the hand that can eventually cause contractures of the affected fingers. Transforming growth factor- β1 (TGF-β1) has been reported to play a key role in DD pathology. Increased expression of TGF-β1 has shown to be the m...

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Detalles Bibliográficos
Autores principales: Zhou, Chaoming, Zeldin, Yael, Baratz, Mark E., Kathju, Sandeep, Satish, Latha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441192/
https://www.ncbi.nlm.nih.gov/pubmed/30927912
http://dx.doi.org/10.1186/s12891-019-2486-3

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