Cargando…

Pixel: a content management platform for quantitative omics data

BACKGROUND: In biology, high-throughput experimental technologies, also referred as “omics” technologies, are increasingly used in research laboratories. Several thousands of gene expression measurements can be obtained in a single experiment. Researchers are routinely facing the challenge to annota...

Descripción completa

Detalles Bibliográficos
Autores principales: Denecker, Thomas, Durand, William, Maupetit, Julien, Hébert, Charles, Camadro, Jean-Michel, Poulain, Pierre, Lelandais, Gaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441322/
https://www.ncbi.nlm.nih.gov/pubmed/30944779
http://dx.doi.org/10.7717/peerj.6623
_version_ 1783407534920433664
author Denecker, Thomas
Durand, William
Maupetit, Julien
Hébert, Charles
Camadro, Jean-Michel
Poulain, Pierre
Lelandais, Gaëlle
author_facet Denecker, Thomas
Durand, William
Maupetit, Julien
Hébert, Charles
Camadro, Jean-Michel
Poulain, Pierre
Lelandais, Gaëlle
author_sort Denecker, Thomas
collection PubMed
description BACKGROUND: In biology, high-throughput experimental technologies, also referred as “omics” technologies, are increasingly used in research laboratories. Several thousands of gene expression measurements can be obtained in a single experiment. Researchers are routinely facing the challenge to annotate, store, explore and mine all the biological information they have at their disposal. We present here the Pixel web application (Pixel Web App), an original content management platform to help people involved in a multi-omics biological project. METHODS: The Pixel Web App is built with open source technologies and hosted on the collaborative development platform GitHub (https://github.com/Candihub/pixel). It is written in Python using the Django framework and stores all the data in a PostgreSQL database. It is developed in the open and licensed under the BSD 3-clause license. The Pixel Web App is also heavily tested with both unit and functional tests, a strong code coverage and continuous integration provided by CircleCI. To ease the development and the deployment of the Pixel Web App, Docker and Docker Compose are used to bundle the application as well as its dependencies. RESULTS: The Pixel Web App offers researchers an intuitive way to annotate, store, explore and mine their multi-omics results. It can be installed on a personal computer or on a server to fit the needs of many users. In addition, anyone can enhance the application to better suit their needs, either by contributing directly on GitHub (encouraged) or by extending Pixel on their own. The Pixel Web App does not provide any computational programs to analyze the data. Still, it helps to rapidly explore and mine existing results and holds a strategic position in the management of research data.
format Online
Article
Text
id pubmed-6441322
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher PeerJ Inc.
record_format MEDLINE/PubMed
spelling pubmed-64413222019-04-03 Pixel: a content management platform for quantitative omics data Denecker, Thomas Durand, William Maupetit, Julien Hébert, Charles Camadro, Jean-Michel Poulain, Pierre Lelandais, Gaëlle PeerJ Computational Biology BACKGROUND: In biology, high-throughput experimental technologies, also referred as “omics” technologies, are increasingly used in research laboratories. Several thousands of gene expression measurements can be obtained in a single experiment. Researchers are routinely facing the challenge to annotate, store, explore and mine all the biological information they have at their disposal. We present here the Pixel web application (Pixel Web App), an original content management platform to help people involved in a multi-omics biological project. METHODS: The Pixel Web App is built with open source technologies and hosted on the collaborative development platform GitHub (https://github.com/Candihub/pixel). It is written in Python using the Django framework and stores all the data in a PostgreSQL database. It is developed in the open and licensed under the BSD 3-clause license. The Pixel Web App is also heavily tested with both unit and functional tests, a strong code coverage and continuous integration provided by CircleCI. To ease the development and the deployment of the Pixel Web App, Docker and Docker Compose are used to bundle the application as well as its dependencies. RESULTS: The Pixel Web App offers researchers an intuitive way to annotate, store, explore and mine their multi-omics results. It can be installed on a personal computer or on a server to fit the needs of many users. In addition, anyone can enhance the application to better suit their needs, either by contributing directly on GitHub (encouraged) or by extending Pixel on their own. The Pixel Web App does not provide any computational programs to analyze the data. Still, it helps to rapidly explore and mine existing results and holds a strategic position in the management of research data. PeerJ Inc. 2019-03-27 /pmc/articles/PMC6441322/ /pubmed/30944779 http://dx.doi.org/10.7717/peerj.6623 Text en ©2019 Denecker et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Computational Biology
Denecker, Thomas
Durand, William
Maupetit, Julien
Hébert, Charles
Camadro, Jean-Michel
Poulain, Pierre
Lelandais, Gaëlle
Pixel: a content management platform for quantitative omics data
title Pixel: a content management platform for quantitative omics data
title_full Pixel: a content management platform for quantitative omics data
title_fullStr Pixel: a content management platform for quantitative omics data
title_full_unstemmed Pixel: a content management platform for quantitative omics data
title_short Pixel: a content management platform for quantitative omics data
title_sort pixel: a content management platform for quantitative omics data
topic Computational Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441322/
https://www.ncbi.nlm.nih.gov/pubmed/30944779
http://dx.doi.org/10.7717/peerj.6623
work_keys_str_mv AT deneckerthomas pixelacontentmanagementplatformforquantitativeomicsdata
AT durandwilliam pixelacontentmanagementplatformforquantitativeomicsdata
AT maupetitjulien pixelacontentmanagementplatformforquantitativeomicsdata
AT hebertcharles pixelacontentmanagementplatformforquantitativeomicsdata
AT camadrojeanmichel pixelacontentmanagementplatformforquantitativeomicsdata
AT poulainpierre pixelacontentmanagementplatformforquantitativeomicsdata
AT lelandaisgaelle pixelacontentmanagementplatformforquantitativeomicsdata