Interrogation of human hematopoiesis at single-cell and single-variant resolution

Widespread linkage disequilibrium and incomplete annotation of cell-to-cell state variation represent substantial challenges to elucidating mechanisms of trait-associated genetic variation. Here, we perform genetic fine-mapping for blood cell traits in the UK Biobank to identify putative causal vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Ulirsch, Jacob C., Lareau, Caleb A., Bao, Erik L., Ludwig, Leif S., Guo, Michael H., Benner, Christian, Satpathy, Ansuman T., Kartha, Vinay K., Salem, Rany M., Hirschhorn, Joel N., Finucane, Hilary K., Aryee, Martin J., Buenrostro, Jason D., Sankaran, Vijay G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441389/
https://www.ncbi.nlm.nih.gov/pubmed/30858613
http://dx.doi.org/10.1038/s41588-019-0362-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441389/
https://www.ncbi.nlm.nih.gov/pubmed/30858613
http://dx.doi.org/10.1038/s41588-019-0362-6

Ejemplares similares